Wegovy vs Mounjaro: Which Weight Loss Injection Is Right for You?

Thinking about starting a weight loss injection but not sure whether Wegovy or Mounjaro is the better fit? 

You’re not alone.

Both are popular options for people who want real results—especially if you’ve struggled to lose weight with diet and exercise alone. 

At Nulevel Wellness Medspa we offer both semaglutide (Wegovy) and tirzepatide (Mounjaro) as part of personalized weight loss plans.

Let’s break down the differences, what the research says, and how we can help you choose the right path forward.

What Are Wegovy and Mounjaro?

Wegovy is a prescription weight loss injection made with semaglutide. 

It works by mimicking a hormone that helps control hunger and blood sugar. 

Mounjaro contains tirzepatide, which targets two hormones: GLP-1 and GIP. 

It was originally approved to treat type 2 diabetes, but doctors now often prescribe it off-label for weight loss because of how effective it is.

If you’re looking for a medical solution to support your weight loss journey, both of these medications may be an option—and we offer them right here at Nulevel.

Wegovy vs Mounjaro: What’s the Difference?

Here’s a quick comparison to help you understand how these two treatments stack up:

• Mechanism of Action:
  • Wegovy (semaglutide) works on the GLP-1 hormone
  • Mounjaro (tirzepatide) works on GLP-1 and GIP hormones
• Average Weight Loss:
  • Wegovy: about 15% of body weight
  • Mounjaro: up to 20% of body weight in some studies
• How It’s Taken: Both are weekly injections you give yourself at home.
• Side Effects: Common side effects of semaglutide and tirzepatide include nausea, bloating, fatigue, and constipation. Mounjaro side effects may cause slightly more constipation, but this varies from person to person.

Which One Works Better for Weight Loss?

Clinical studies have shown that Mounjaro (tirzepatide) tends to help people lose more weight than Wegovy (semaglutide).

On average:

• Wegovy users lost around 15% of their body weight
  
• Mounjaro users lost closer to 20%
  

But that doesn’t mean Mounjaro is always the better choice. 

Everyone responds differently. 

Some people feel better on semaglutide. 

Others get faster results with tirzepatide. 

What really matters is choosing what works best for your body.

That’s why we offer both options and work closely with you to monitor results, adjust your plan, and help you stay on track.

What About Side Effects?

Most side effects are related to digestion and tend to be more noticeable when you first start. 

These can include:

• Nausea
  
• Fatigue
  
• Constipation
  
• Diarrhea
  
• Reduced appetite
  

We help our clients manage semaglutide and tirzepatide side effects through smart dosing and support. 

If something’s bothering you, we’re here to make adjustments and help you feel your best throughout your treatment.

How to Choose the Right Weight Loss Injection

Choosing between Wegovy and Mounjaro doesn’t have to be complicated. 

Here are a few things we consider when helping our clients decide which is the best injection for weight loss:

• Do you have type 2 diabetes or insulin resistance?
  
• Are you concerned about side effects like nausea or fatigue?
  
• What’s your weight loss goal?
  
• Is affordability or insurance coverage a factor?
  

You don’t need to figure this out on your own. 

We’ll guide you based on your body, your needs, and your goals.

How Nulevel Wellness Medspa Can Help

We’re not a one-size-fits-all clinic. 

When you work with us, you’ll get:

• A personalized plan using semaglutide or tirzepatide
  
• Help managing side effects and tracking progress
  
• Access to both brand-name and compounded medications
  
• Ongoing support from a team that wants to see you succeed
  

We’ve helped people reach their weight loss goals using proven, medical solutions—and we’re ready to help you too.

Conclusion: Wegovy vs Mounjaro

If you’re comparing Wegovy vs Mounjaro, we can help you choose the right path—and support you the entire way.

Schedule your consultation with Nulevel Wellness Medspa today and let’s build a weight loss plan that actually works for your body and your lifestyle.

FAQs: Wegovy vs Mounjaro

What are the benefits of tirzepatide?
Tirzepatide, the active ingredient in Mounjaro, has several benefits for people looking to lose weight or manage blood sugar. It helps reduce appetite, improve insulin sensitivity, and support long-term weight loss. Studies have shown that tirzepatide may lead to greater weight loss than other GLP-1 medications, including semaglutide. Many people also report feeling fuller sooner and having better control over cravings while using it.

Is Mounjaro better than Wegovy for weight loss?
Mounjaro has shown slightly better weight loss results in clinical trials compared to Wegovy. On average, people using tirzepatide lost up to 20% of their body weight, while those on semaglutide lost closer to 15%. That said, “better” depends on how your body responds. Some people tolerate semaglutide better or see faster results with it. At Nulevel Wellness Medspa, we help you figure out which one works best for your individual goals.

Can you switch from Wegovy to Mounjaro?
Yes, switching from Wegovy to Mounjaro is possible, and many people do it if they’re not getting the results they want or if side effects are an issue. If you’re thinking about switching, it’s important to do it with the help of a medical provider. We’ll look at your progress, adjust your dosing carefully, and guide you through the transition to make sure it’s smooth and safe.

Why am I not losing weight on Mounjaro?
If you’re not losing weight on Mounjaro, there could be a few reasons. It might be related to how your body is reacting to the medication, your dose level, or lifestyle factors like stress, sleep, or what you’re eating. It’s also possible that the medication just isn’t the right match for your system. At Nulevel, we take a hands-on approach—if you’re not seeing progress, we make adjustments and work with you to troubleshoot what’s holding you back.

Is Wegovy a lifelong medication?
Wegovy isn’t necessarily a lifelong medication, but long-term use may be needed to maintain weight loss. Like any chronic condition, obesity often requires ongoing treatment. Some people stay on semaglutide longer to help keep the weight off, while others taper off over time with the help of a provider. At Nulevel, we build your treatment plan with both your short-term results and long-term health in mind.

Do you gain weight back after stopping Mounjaro?
It’s possible to regain weight after stopping Mounjaro if lifestyle habits don’t continue. The medication helps regulate hunger and insulin levels, so once it’s stopped, your body may return to old patterns. That’s why we always focus on helping you build sustainable habits alongside the medication. If you stop taking tirzepatide, we’ll work with you to maintain your progress through other supportive strategies.